Trial Profile

A Phase 1, First-in-human (FIH), Dose-Escalation and Dose-Optimization Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 13 Jan 2026

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At a glance

08 Jan 2026 Status changed from planning to recruiting.
18 Dec 2025 According to Cartography Biosciences media release, the company today announced the U.S. Food and Drug Administration (FDA) has approved the Companys Investigational New Drug (IND) application for CBI-1214.The company plans to initiate this trial in the first quarter of 2026.
10 Nov 2025 New trial record

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