Trial Profile

A Phase IIa trial of TTX MC138 in patients with colorectal cancer who have completed standard curative-intent therapy and have positive markers for circulating tumor DNA (ctDNA)

Status: Planning

Phase of Trial: Phase II

Latest Information Update: 17 Feb 2026

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At a glance

05 Feb 2026 According to a TransCode Therapeutics media release, the company announced the submission to the U.S. FDA of an Investigational New Drug (IND) application amendment for this planned trial.
11 Dec 2025 According to a TransCode Therapeutics media release, the Phase 2a portion of the trial is planned to begin in the first half of 2026 and will be led by Principal Investigator Dr. Paula Pohlmann of MD Anderson Cancer Center.
12 Nov 2025 New trial record

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