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Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial Comparing Standard of Care Adjuvant Temozolomide With or Without 5-Aminolevulinic Acid (5-ALA) With Concomitant Low Intensity Diffuse Ultrasound (LIDU) Sonodynamic Therapy (SDT) System In Patients With Newly Diagnosed Glioblastoma After Completion of Chemoradiotherapy

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Trial Profile

Multi-Center, Randomized, Double-Blind, Placebo-Controlled Trial Comparing Standard of Care Adjuvant Temozolomide With or Without 5-Aminolevulinic Acid (5-ALA) With Concomitant Low Intensity Diffuse Ultrasound (LIDU) Sonodynamic Therapy (SDT) System In Patients With Newly Diagnosed Glioblastoma After Completion of Chemoradiotherapy

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Feb 2026

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At a glance

  • Drugs Aminolevulinic acid (Primary)
  • Indications Glioblastoma
  • Focus Therapeutic Use
  • Sponsors Alpheus Medical

Most Recent Events

  • 13 Jan 2026 Planned initiation date changed from 1 Dec 2025 to 1 Jan 2026.
  • 13 Jan 2026 Status changed from not yet recruiting to recruiting.
  • 13 Nov 2025 New trial record

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