Trial Profile

A Phase 3, Randomized, Double-blind, Efficacy and Safety Study Comparing Orelabrutinib to Placebo in Patients With Non-active Secondary Progressive Multiple Sclerosis

Status: Not yet recruiting

Phase of Trial: Phase III

Latest Information Update: 22 Jan 2026

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At a glance

Drugs Orelabrutinib (Primary)
Indications Multiple sclerosis
Focus Registrational; Therapeutic Use
Sponsors Zenas BioPharma

Most Recent Events

12 Jan 2026 Planned number of patients changed from 330 to 990.
14 Dec 2025 Status changed from planning to not yet recruiting.
14 Dec 2025 According to InnoCare Pharma media release, company has received approval to conduct a phase 3 registrational trial.

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