Trial Profile

A Multicenter, Multi-Part, Phase 1/2 Study of EIK1005 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors, Including Checkpoint Inhibitor Naïve Participants With Microsatellite Instability High (MSI-H) or Mismatch Repair Deficient (dMMR) Tumors

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 09 Dec 2025

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At a glance

Drugs EIK 1005 (Primary) ; Pembrolizumab
Indications Colorectal cancer; Endometrial cancer; Gastric cancer; Oesophageal cancer; Solid tumours
Focus Adverse reactions
Sponsors Eikon Therapeutics

14 Nov 2025 New trial record
15 Oct 2025 According to Eikon Therapeutics media release, EIK1005 is expected to begin Phase 1 clinical testing in Q4, 2025

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