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Phase 1 first in human single-ascending dose trial study evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of a subcutaneous dose of VIAL-INHBE

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Trial Profile

Phase 1 first in human single-ascending dose trial study evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of a subcutaneous dose of VIAL-INHBE

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Jan 2026

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At a glance

  • Drugs VIAL INHBE (Primary)
  • Indications Obesity
  • Focus Adverse reactions; First in man; Pharmacokinetics

Most Recent Events

  • 16 Dec 2025 According to Vial media release, data from this study are expected to inform dose selection and design for future trials in patients with obesity and obesity-related cardiometabolic disease.
  • 19 Nov 2025 New trial record
  • 23 Oct 2025 According to Vial media release, company announced the initiation of Phase 1 trial for a novel INHBE (Activin E) siRNA (VIAL INHBE).

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