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A phase 3 study of Ondansetron/Pramipexole in treatment resistant depression.

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Trial Profile

A phase 3 study of Ondansetron/Pramipexole in treatment resistant depression.

Status: Planning
Phase of Trial: Phase III

Latest Information Update: 17 Nov 2025

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At a glance

  • Drugs Ondansetron/Pramipexole (Primary)
  • Indications Treatment-resistant depressive disorder
  • Focus Registrational; Therapeutic Use

Most Recent Events

  • 17 Nov 2025 According to a Alto Neuroscience media release, Successful outcome from recent FDA meeting guides Alto's plan to accelerate development of ALTO-207, with capital from a $50 million private placement financing expected to enable the company to initiate a Phase 3 study by early 2027 following Phase 3 readiness work, protocol alignment and alignment with the FDA on the planned study design.
  • 17 Nov 2025 New trial record

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