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A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

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Trial Profile

A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 16 Feb 2026

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At a glance

  • Drugs INCA 33890 (Primary) ; Bevacizumab; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Incyte Corporation

Most Recent Events

  • 16 Feb 2026 Status changed from not yet recruiting to recruiting.
  • 18 Nov 2025 New trial record
  • 19 Oct 2025 According to Incyte corporation media release, Incyte plans to initiate a registrational program for INCA33890 in MSS colorectal cancer in 2026.

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