A Double-blind, Randomized, Psychoactive Placebo-controlled Study to Evaluate the Efficacy and Safety of Intranasal Esketamine 84 mg in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder in Adolescent Participants With Acute Suicidal Ideation or Behavior
Latest Information Update: 18 Nov 2025
At a glance
- Drugs Esketamine (Primary) ; Midazolam
- Indications Major depressive disorder; Suicidal ideation
- Focus Registrational; Therapeutic Use
- Acronyms AVENUE
- Sponsors Janssen Research & Development
Most Recent Events
- 18 Nov 2025 New trial record