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A Phase 2 multi-center, randomized, double-blind, placebo-controlled trial of LB-102 for the treatment of bipolar depression

Trial Profile

A Phase 2 multi-center, randomized, double-blind, placebo-controlled trial of LB-102 for the treatment of bipolar depression

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Feb 2026

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At a glance

  • Drugs Amisulpride (Primary)
  • Indications Bipolar depression; Bipolar I disorders
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ILLUMINATE-1

Most Recent Events

  • 26 Jan 2026 Status changed from planning to recruiting.
  • 26 Jan 2026 According to LB Pharmaceuticals media release, the company announced initiation of Phase 2 bipolar depression trial initiation follows positive Phase 2 results in acute schizophrenia, topline data expected in 1Q 2028. The trial will enroll at approximately 30 sites in the U.S.
  • 18 Nov 2025 New trial record

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