Trial Profile

A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination With FOLFOX Versus Bevacizumab in Combination With FOLFOX for the First-line Treatment of Metastatic Colorectal Cancer

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 21 Nov 2025

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At a glance

18 Nov 2025 New trial record
13 Nov 2025 Status changed from planning to recruiting.
20 Oct 2025 According to Summit therapeutics media release, the company anticipates Initiation of HARMONi-GI3, a New Study in 1L CRC: Summit to Initiate an Additional Set of Phase III Clinical Trials with Details to Come in Q1 2026

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