Trial Profile

A Phase 3, Randomized, Open-Label, Multicenter Study of Amivantamab in Addition to Carboplatin and Pembrolizumab, Compared to Standard of Care Platinum and Pembrolizumab and 5-FU, in Participants With Treatment-Naïve Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Status: Recruiting

Phase of Trial: Phase III

Latest Information Update: 18 Feb 2026

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At a glance

Drugs Amivantamab (Primary) ; Carboplatin; Cisplatin; Fluorouracil; Pembrolizumab
Indications Head and neck cancer; Squamous cell cancer
Focus Registrational; Therapeutic Use
Acronyms OrigAMI-5
Sponsors Janssen Research & Development

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