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A Comparison of PK and PD Responses Following Single and Repeat Administration of Epinephrine Nasal FMXIN002 4.0 mg and EpiPen 0.3 mg, in Healthy Adults With Allergic Rhinitis

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Trial Profile

A Comparison of PK and PD Responses Following Single and Repeat Administration of Epinephrine Nasal FMXIN002 4.0 mg and EpiPen 0.3 mg, in Healthy Adults With Allergic Rhinitis

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Jan 2026

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At a glance

  • Drugs Epinephrine (Primary) ; Epinephrine (Primary)
  • Indications Anaphylaxis
  • Focus Pharmacodynamics; Pharmacokinetics
  • Sponsors Nasus Pharma

Most Recent Events

  • 22 Dec 2025 According to Nasus Pharma media release, the company dosed the first patient in an open-label, fixed-sequence trial designed to evaluate the pharmacokinetic parameters and hemodynamic responses of NS002 compared to EpiPen in up to 50 healthy adults with a history of allergic rhinitis. We expect to report an interim analysis early in the first quarter of 2026.
  • 19 Nov 2025 New trial record

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