A single-arm, multicenter, open-label, Phase I/II trial of Allo-QuadCAR01-T, an allogeneic CAR-T-cell therapy targeting CD19 and CD20, for the treatment of relapsed or refractory B-cell malignancies - AVC-203-01
Latest Information Update: 16 Dec 2025
At a glance
- Drugs AVC 203 (Primary)
- Indications B-cell leukaemia; B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma
- Focus Adverse reactions; First in man; Registrational; Therapeutic Use
- Acronyms QUADvance
- Sponsors AvenCell Therapeutics
Most Recent Events
- 04 Dec 2025 According to Avencell media release,The phase Ia dose escalation study is expected to be followed by a phase Ib dose expansion study and a Phase II pivotal trial.
- 04 Dec 2025 According to Avencell media release, the FDA and the European Medicines Agency (EMA) have cleared the companys IND and approved the Clinical Trial Application (CTA)for this trial.
- 19 Nov 2025 New trial record