Prospective, Multi Country, Observational Study of Clinical Outcomes in EGFR-mutated, Advanced Non-Small Cell Lung Cancer (NSCLC) Patients Treated With Approved Amivantamab-containing Regimens Under Standard Clinical Practice
Latest Information Update: 18 Feb 2026
At a glance
- Drugs Amivantamab (Primary) ; Carboplatin (Primary) ; Pemetrexed (Primary)
- Indications Non-small cell lung cancer
- Focus Therapeutic Use
- Acronyms LEPIDOPTERA
- Sponsors Janssen Research & Development
Most Recent Events
- 16 Jan 2026 Planned End Date changed from 28 Nov 2030 to 17 Dec 2030.
- 24 Dec 2025 Number of treatment arms are reduced from 3 to 2 by the removal of "first-line treatment with Amivantamab with carboplatin and pemetrexed" cohort.
- 24 Dec 2025 Planned number of patients changed from 460 to 380.