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A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

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Trial Profile

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Mar 2026

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At a glance

  • Drugs Ribupatide (Primary)
  • Indications Obesity; Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms KaiNETIC-2
  • Sponsors Kailera Therapeutics

Most Recent Events

  • 20 Jan 2026 Status changed from not yet recruiting to recruiting.
  • 13 Jan 2026 According to Kailera Therapeutics media release, announced the randomization of the first participants in the KaiNETIC global Phase 3 clinical program of ribupatide (also known as KAI-9531), an investigational once-weekly injectable dual GLP-1/GIP receptor agonist peptide, for the treatment of people living with obesity or overweight.
  • 21 Nov 2025 New trial record

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