Trial Profile

A Single-arm, Single-center, Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Bevacizumab and Chemotherapy (FOLFOXIRI) as First-line Treatment for MSS/pMMR Metastatic Colorectal Cancer With BRAF V600E Mutation

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 21 Jan 2026

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At a glance

Drugs Bevacizumab (Primary) ; Capecitabine (Primary) ; Fluorouracil (Primary) ; Iparomlimab/tuvonralimab (Primary) ; Irinotecan (Primary)
Indications Adenocarcinoma; Colon cancer
Focus Therapeutic Use

08 Jan 2026 Planned End Date changed from 1 Dec 2027 to 1 Feb 2028.
08 Jan 2026 Planned primary completion date changed from 1 Dec 2026 to 1 Feb 2027.
08 Jan 2026 Planned initiation date changed from 1 Dec 2025 to 1 Feb 2026.

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