Trial Profile

Peri-Hematopoietic Cell Transplantation Ruxolitinib in Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 24 Feb 2026

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At a glance

Drugs Busulfan (Primary) ; Cyclophosphamide (Primary) ; Fludarabine (Primary) ; Melphalan (Primary) ; Methotrexate (Primary) ; Ruxolitinib (Primary) ; Stem cell therapies (Primary) ; Tacrolimus (Primary) ; Tacrolimus (Primary)
Indications Graft-versus-host disease; Myelodysplastic syndromes; Myelofibrosis; Myeloproliferative disorders
Focus Therapeutic Use

Most Recent Events

22 Jan 2026 Planned initiation date (estimated date of first patient enrollment) changed from 1 May 2026 to 21 Feb 2026.
22 Jan 2026 Status changed from not yet recruiting to recruiting.
21 Nov 2025 New trial record

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