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a Randomized, Controlled, Double-Blind, Multicenter Phase III Clinical Trial of HRS-4642 in Combination With Chemotherapy Versus Placebo in Combination With Chemotherapy as First-Line Therapy in Patients With Advanced or Metastatic Pancreatic Carcinoma Harboring KRAS G12D Gene Mutation

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Trial Profile

a Randomized, Controlled, Double-Blind, Multicenter Phase III Clinical Trial of HRS-4642 in Combination With Chemotherapy Versus Placebo in Combination With Chemotherapy as First-Line Therapy in Patients With Advanced or Metastatic Pancreatic Carcinoma Harboring KRAS G12D Gene Mutation

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Nov 2025

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At a glance

  • Drugs Gemcitabine (Primary) ; HRS 4642 (Primary) ; Paclitaxel (Primary)
  • Indications Carcinoma; Pancreatic cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Jiangsu Hengrui Medicine Co.

Most Recent Events

  • 26 Nov 2025 New trial record

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