Trial Profile

A Study to Evaluate the Effect of Multiple Oral Doses of Diltiazem on the Single-Dose Pharmacokinetics of Nemtabrutinib in Healthy Participants

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 10 Feb 2026

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At a glance

Drugs Nemtabrutinib (Primary) ; Diltiazem
Indications Chronic lymphocytic leukaemia; Follicular lymphoma; Haematological malignancies; Richter's syndrome
Focus Pharmacokinetics
Sponsors Merck Sharp & Dohme Corp.

Most Recent Events

23 Jan 2026 Planned End Date changed from 13 Feb 2026 to 12 Apr 2026.
23 Jan 2026 Planned primary completion date changed from 1 Feb 2026 to 12 Apr 2026.
12 Dec 2025 Status changed from not yet recruiting to recruiting.

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