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A Phase-1, Parallel-Design, Open-Label, Randomized, Multiple-Dose Escalation Study to Investigate the Safety, Tolerability, and Pharmacokinetics of LY3549492 in Healthy Participants With Overweight or Obesity

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Trial Profile

A Phase-1, Parallel-Design, Open-Label, Randomized, Multiple-Dose Escalation Study to Investigate the Safety, Tolerability, and Pharmacokinetics of LY3549492 in Healthy Participants With Overweight or Obesity

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Feb 2026

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At a glance

  • Drugs Naperiglipron (Primary)
  • Indications Obesity
  • Focus Adverse reactions
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 17 Feb 2026 Planned End Date changed from 1 Feb 2026 to 1 Jul 2026.
  • 17 Feb 2026 Planned primary completion date changed from 1 Feb 2026 to 1 Jul 2026.
  • 26 Nov 2025 New trial record

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