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A Randomized Phase II Study Evaluating Upfront SRT to All Brain Metastases Followed by Ivonescimab Plus Chemotherapy Versus Upfront Ivonescimab Plus Chemotherapy in Patients With Asymptomatic Active Brain Metastases From NSCLC

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Trial Profile

A Randomized Phase II Study Evaluating Upfront SRT to All Brain Metastases Followed by Ivonescimab Plus Chemotherapy Versus Upfront Ivonescimab Plus Chemotherapy in Patients With Asymptomatic Active Brain Metastases From NSCLC

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 27 Nov 2025

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At a glance

  • Drugs Ivonescimab (Primary) ; Pemetrexed (Primary) ; Antineoplastics
  • Indications Brain metastases; Non-small cell lung cancer
  • Focus Therapeutic Use

Most Recent Events

  • 27 Nov 2025 New trial record

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