Trial Profile

A Phase 1, Open-label, Single-sequence, 2-period Study to Evaluate the Effect of Multiple Doses of Vorasidenib on the Pharmacokinetics of a Single Dose of Sensitive Index Substrates of Cytochrome P450 2B6, 2C8, 2C9, 2C19, 3A4, and Breast Cancer Resistance Protein in Healthy Adult Participants

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 12 Jan 2026

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At a glance

Drugs Vorasidenib (Primary) ; Bupropion; Flurbiprofen; Midazolam; Omeprazole; Repaglinide; Rosuvastatin
Indications Astrocytoma; Glioma; Oligodendroglioma; Solid tumours
Focus Pharmacokinetics
Sponsors Servier International Research Institute

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