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An Open-label, Fixed-sequence Study to Assess the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants

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Trial Profile

An Open-label, Fixed-sequence Study to Assess the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 28 Nov 2025

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At a glance

  • Drugs Capivasertib (Primary) ; Dextromethorphan (Primary)
  • Indications Breast cancer; Endometrial cancer; Fallopian tube cancer; Gastric cancer; HER2 negative breast cancer; Meningioma; Non-Hodgkin's lymphoma; Ovarian cancer; Peritoneal cancer; Prostate cancer; Solid tumours; Triple negative breast cancer
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

Most Recent Events

  • 28 Nov 2025 New trial record

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