Trial Profile

A Phase-1, Open-label Randomized, 4-treatment, 4-period Crossover Study to Evaluate the Pharmacokinetics, Relative Bioavailability, Safety and Tolerability of Single Doses of Dihydroergotamine Mesylate (DHE) Inhalation Powder, DHE Intravenous (IV), and DHE Nasal Spray in Healthy Adult Subjects.

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 28 Nov 2025

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At a glance

Drugs Dihydroergotamine mesilate (Primary) ; Dihydroergotamine mesilate (Primary) ; Dihydroergotamine mesilate (Primary) ; Metoclopramide
Indications Migraine
Focus Pharmacokinetics
Sponsors Aspeya

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