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Phase 2 Study of Venetoclax-containing Therapy in Combination With HLA-mismatched Mobilized Peripheral Blood Mononuclear Cell Infusion for Intermediate-risk and Higher Myelodysplastic Syndromes

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Trial Profile

Phase 2 Study of Venetoclax-containing Therapy in Combination With HLA-mismatched Mobilized Peripheral Blood Mononuclear Cell Infusion for Intermediate-risk and Higher Myelodysplastic Syndromes

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 01 Dec 2025

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At a glance

  • Drugs Azacitidine (Primary) ; Blood mononuclear cell therapy (Primary) ; Decitabine (Primary) ; Venetoclax (Primary)
  • Indications Myelodysplastic syndromes
  • Focus Therapeutic Use

Most Recent Events

  • 01 Dec 2025 New trial record
  • 25 Nov 2025 Primary efficacy end-point "Complete remission (CR)" is removed and replaced by "Overall response rate (ORR)".

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