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A Phase 2A/B, Multi-center, Open-Label Study Evaluating the Efficacy and Safety of Dabogratinib (TYRA-300) in Participants With Low Grade Upper Tract Urothelial Carcinoma (SURF303)

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Trial Profile

A Phase 2A/B, Multi-center, Open-Label Study Evaluating the Efficacy and Safety of Dabogratinib (TYRA-300) in Participants With Low Grade Upper Tract Urothelial Carcinoma (SURF303)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Jan 2026

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At a glance

  • Drugs Dabogratinib (Primary)
  • Indications Carcinoma; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms SURF 303; SURF-303
  • Sponsors Tyra Biosciences

Most Recent Events

  • 16 Jan 2026 Status changed from not yet recruiting to recruiting.
  • 02 Dec 2025 New trial record
  • 05 Nov 2025 According to Tyra Biosciences media release, the trial is planned to be initiated in 2026.

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