Trial Profile

A Phase 1b, Open-label, Multicenter, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of AG-181 in Subjects With Phenylketonuria

Status: Not yet recruiting

Phase of Trial: Phase I

Latest Information Update: 05 Feb 2026

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At a glance

Drugs AG 181 (Primary)
Indications Phenylketonuria
Focus Adverse reactions
Sponsors Agios Pharmaceuticals

Most Recent Events

12 Jan 2026 According to an Agios Pharmaceuticals media release, data from this trial will be presented at J.P. Morgan Healthcare Conference on Wednesday, January 14, 2026.
12 Jan 2026 According to Agios Pharmaceuticals, Inc media release, the company expects to initiate a Phase 1b proof-of-mechanism trial of AG-181 in patients with PKU in the first half of 2026 and to confirm proof of mechanism in the second half of 2026.
02 Dec 2025 New trial record

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