Trial Profile

An Investigator-initiated, Open-Label Clinical Study of a mRNA Vaccine Encoding Tumor-Specific Circular RNA Antigens in Combination With Anti-PD-1 Monoclonal Antibody in Patients With Advanced Solid Tumors

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 02 Dec 2025

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At a glance

Drugs CircFAM53B mRNA vaccine (Primary) ; Toripalimab (Primary)
Indications Advanced breast cancer; Colorectal cancer; Malignant melanoma; Non-small cell lung cancer; Pancreatic cancer; Solid tumours
Focus Therapeutic Use

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