Trial Profile

KEYMAKER-U01 Substudy 01J: A Randomized Phase 2 Umbrella Study With Rolling Arms of Investigational Agents for First-line Treatment of Participants With Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With KRAS G12C Mutations

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 03 Dec 2025

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At a glance

Drugs Calderasib (Primary) ; Carboplatin; Cetuximab; Pembrolizumab; Pemetrexed
Indications Non-small cell lung cancer
Focus Adverse reactions; Therapeutic Use
Acronyms KEYMAKER-U01J
Sponsors Merck Sharp & Dohme Corp.

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