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A Phase 1 Study of Rebecsinib, a Spliceosome Modulator That Inhibits ADAR1, in Patients With Relapsed or Refractory Secondary Acute Myeloid Leukemia or Higher-Risk Myelofibrosis

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Trial Profile

A Phase 1 Study of Rebecsinib, a Spliceosome Modulator That Inhibits ADAR1, in Patients With Relapsed or Refractory Secondary Acute Myeloid Leukemia or Higher-Risk Myelofibrosis

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 04 Feb 2026

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At a glance

  • Drugs Rebecsinib (Primary)
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes; Myeloproliferative disorders
  • Focus Adverse reactions
  • Sponsors Aspera Biomedicines

Most Recent Events

  • 03 Dec 2025 New trial record

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