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Phase I clinical trial of cereblon E3 ligase modulator (CELMoD) .

Trial Profile

Phase I clinical trial of cereblon E3 ligase modulator (CELMoD) .

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 03 Dec 2025

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At a glance

  • Drugs Cereblon-E3-ligase-modulator-Bristol-Myers-Squibb/Evotec-SE (Primary)
  • Indications Unspecified
  • Focus Adverse reactions

Most Recent Events

  • 03 Dec 2025 New trial record
  • 12 Nov 2025 According to an Evotec SE media release, the company announced that it has received a US$ 5 m milestone payment from Bristol Myers Squibb, following the acceptance of an Investigational New Drug application by the U.S. Food and Drug Administration in their strategic protein degradation partnership. The company plans to initiate Phase 1 clinical trial in 2026.

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