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Ruxolitinib-Enhanced Conditioning for Pediatric and Young Adult Patients With Symptomatic Sickle Cell Disease Undergoing Haploidentical Hematopoietic Cell Transplantation

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Trial Profile

Ruxolitinib-Enhanced Conditioning for Pediatric and Young Adult Patients With Symptomatic Sickle Cell Disease Undergoing Haploidentical Hematopoietic Cell Transplantation

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 04 Dec 2025

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At a glance

  • Drugs Ruxolitinib (Primary) ; Antithymocyte globulin; Calcineurin inhibitors; Cyclophosphamide; Fludarabine; Sirolimus; Thiotepa
  • Indications Sickle cell anaemia
  • Focus Therapeutic Use
  • Acronyms RUX-HAPLO

Most Recent Events

  • 04 Dec 2025 New trial record

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