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Acute Severe Ulcerative Colitis- Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction While Transitioning Away From the Emergency Setting (ACUTE): A Phase IV, Single Center, Partially Blinded, Randomized Study

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Trial Profile

Acute Severe Ulcerative Colitis- Upadacitinib Combined With Corticosteroids vs Corticosteroid Monotherapy Induction While Transitioning Away From the Emergency Setting (ACUTE): A Phase IV, Single Center, Partially Blinded, Randomized Study

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 05 Feb 2026

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At a glance

  • Drugs Upadacitinib (Primary) ; Methylprednisolone; Prednisolone; Prednisone
  • Indications Ulcerative colitis
  • Focus Therapeutic Use
  • Acronyms ACUTE

Most Recent Events

  • 02 Feb 2026 Status changed from not yet recruiting to completed.
  • 13 Jan 2026 Planned initiation date changed from 1 Dec 2025 to 1 Feb 2026.
  • 05 Dec 2025 New trial record

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