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A Phase 2 Study of Emavusertib in Combination With an Approved Bruton Tyrosine Kinase Inhibitor in Patients With Chronic Lymphocytic Leukemia and Other B-cell Malignancies

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Trial Profile

A Phase 2 Study of Emavusertib in Combination With an Approved Bruton Tyrosine Kinase Inhibitor in Patients With Chronic Lymphocytic Leukemia and Other B-cell Malignancies

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Dec 2025

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At a glance

  • Drugs Emavusertib (Primary) ; Ibrutinib (Primary)
  • Indications Chronic lymphocytic leukaemia; Haematological malignancies
  • Focus Therapeutic Use
  • Sponsors Curis

Most Recent Events

  • 09 Dec 2025 Status changed from planning to not yet recruiting.
  • 09 Dec 2025 New trial record
  • 06 Nov 2025 According to Curis media release, dosing of the first patient expected in late Q4 2025 or early Q1 2026.

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