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A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases

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Trial Profile

A Phase 0/1 Clinical Trial With an Expansion Phase of GSK5764227, a B7-H3-Targeted Antibody-Drug Conjugate (ADC), in Patients With Recurrent Grade 4 Glioma and Patients With Brain Metastases

Status: Recruiting
Phase of Trial: Phase 0

Latest Information Update: 10 Mar 2026

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At a glance

  • Drugs Risvutatug rezetecan (Primary)
  • Indications Brain metastases; Glioma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 06 Mar 2026 Status changed from not yet recruiting to recruiting.
  • 09 Dec 2025 New trial record

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