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Phase 1 multiple-ascending dose (MAD) trial of DT-818 in patients with Myotonic Dystrophy Type-1

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Trial Profile

Phase 1 multiple-ascending dose (MAD) trial of DT-818 in patients with Myotonic Dystrophy Type-1

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 10 Dec 2025

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At a glance

  • Drugs DT 818 (Primary)
  • Indications Myotonic dystrophy
  • Focus Adverse reactions

Most Recent Events

  • 10 Dec 2025 New trial record
  • 05 Nov 2025 According to Design therapeutics media release, the company plans to initiate Plans to Initiate Patient Dosing of DT-818 in Myotonic Dystrophy Type-1 (DM1) in the First Half of 2026 to assess safety and correction of mis-splicing, with splicing data expected in 2027. .

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