A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamic Effects of ANGPTL3 Inhibition With Either Small-Interfering RNA Alone or in Combination With an ANGPTL3 Antibody in Participants With Diabetic Kidney Disease
Latest Information Update: 17 Sep 2026
At a glance
- Drugs ALN ANG3 (Primary) ; Evinacumab
- Indications Diabetic nephropathies
- Focus Therapeutic Use
- Acronyms ANCHOR-POC
- Sponsors Regeneron Pharmaceuticals
Most Recent Events
- 11 Sep 2026 Planned End Date changed from 7 Apr 2028 to 13 Oct 2028.
- 11 Sep 2026 Planned primary completion date changed from 24 Sep 2027 to 13 Oct 2028.
- 04 Feb 2026 Planned End Date changed from 8 Dec 2027 to 7 Apr 2028.