A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamic Effects of ANGPTL3 Inhibition With Either Small-Interfering RNA Alone or in Combination With an ANGPTL3 Antibody in Participants With Diabetic Kidney Disease
Latest Information Update: 09 Feb 2026
At a glance
- Drugs ALN ANG3 (Primary) ; Evinacumab
- Indications Diabetic nephropathies
- Focus Therapeutic Use
- Acronyms ANCHOR-POC
- Sponsors Regeneron Pharmaceuticals
Most Recent Events
- 04 Feb 2026 Planned End Date changed from 8 Dec 2027 to 7 Apr 2028.
- 04 Feb 2026 Planned primary completion date changed from 8 Jun 2027 to 24 Sep 2027.
- 04 Feb 2026 Status changed from not yet recruiting to recruiting.