Trial Profile

A Prospective, Randomized, Open-Label, Parallel-Group Clinical Trial Evaluating the Efficacy and Safety of 125I Seed Interstitial Brachytherapy Combined With Immune Checkpoint Inhibitor Therapy in Patients With Primary, Recurrent, or Metastatic Malignant Tumors Compared With Immune Checkpoint Inhibitor Therapy Alone.

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 19 Jan 2026

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At a glance

Drugs Camrelizumab (Primary) ; Nivolumab (Primary) ; Pembrolizumab (Primary) ; Sintilimab (Primary)
Indications Solid tumours
Focus Therapeutic Use

06 Jan 2026 Planned End Date changed from 1 Dec 2027 to 1 Jan 2028.
06 Jan 2026 Planned primary completion date changed from 1 Dec 2026 to 1 Jan 2027.
06 Jan 2026 Planned initiation date changed from 1 Dec 2025 to 1 Jan 2026.

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