Trial Profile

A Multicenter, Prospective, Phase III Randomized Controlled Trial of PD-1 Antibody Plus FOLFOXIRI Combined With Radiotherapy Versus CAPOX Combined With Radiotherapy as Total Neoadjuvant Therapy for pMMR Locally Advanced Low Rectal Cancer

Status: Not yet recruiting

Phase of Trial: Phase III

Latest Information Update: 16 Dec 2025

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At a glance

Drugs Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary) ; Serplulimab (Primary)
Indications Adenocarcinoma; Rectal cancer
Focus Therapeutic Use

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