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Avacopan Added to Standard-of-care Therapy in ANCA-associated Vasculitis With Severe Kidney Involvement: a Randomized, Placebo-controlled, Double-blinded Multicenter Superiority Study

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Trial Profile

Avacopan Added to Standard-of-care Therapy in ANCA-associated Vasculitis With Severe Kidney Involvement: a Randomized, Placebo-controlled, Double-blinded Multicenter Superiority Study

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 02 Feb 2026

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At a glance

  • Drugs Avacopan (Primary) ; Cyclophosphamide; Methylprednisolone; Prednisolone; Prednisone; Rituximab
  • Indications Anti-neutrophil cytoplasmic antibody-associated vasculitis
  • Focus Therapeutic Use
  • Acronyms REVERSE

Most Recent Events

  • 16 Dec 2025 New trial record

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