Trial Profile

Hyperprogression Upon Cemiplimab Alone or With Chemotherapy in PD-L1 ≥ 50% NSCLC: a Biomarker Guided Phase 2 Trial - HYPERBOLIC Trial

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 18 Dec 2025

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At a glance

Drugs Carboplatin (Primary) ; Cemiplimab (Primary) ; Cisplatin (Primary) ; Paclitaxel (Primary) ; Pemetrexed (Primary)
Indications Non-small cell lung cancer; Squamous cell cancer
Focus Therapeutic Use
Acronyms HYPERBOLIC

Most Recent Events

18 Dec 2025 New trial record

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