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A Randomized, Double-Blind, Placebo-Controlled Phase 2b Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Phase 2b Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Mar 2026

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At a glance

  • Drugs Ecnoglutide (Primary)
  • Indications Obesity
  • Focus Therapeutic Use
  • Acronyms EVOLVE-2
  • Sponsors Verdiva Bio

Most Recent Events

  • 24 Feb 2026 According to a Verdiva Bio, the trial enrolled 200 patients across 22 sites in the US. Topline results expected by the end of 2026.
  • 24 Feb 2026 Status changed from recruiting to active, no longer recruiting, according to a Verdiva Bio.
  • 19 Dec 2025 New trial record

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