Trial Profile

A Multi-center, Double-blind, Placebo-controlled, Phase II Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of RO7268489, a Monoacylglycerol Lipase Inhibitor, as Add-on Therapy to Ocrelizumab, in Participants With Progressive Forms of Multiple Sclerosis

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 06 Feb 2026

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At a glance

03 Feb 2026 Planned initiation date (estimated date of first participant enrollment) changed from 30 Jan 2026 to 28 Feb 2026.
03 Feb 2026 Status changed from not yet recruiting to recruiting.
19 Dec 2025 New trial record

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