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preEMBER: A Phase 2, Open-label Study Evaluating Imlunestrant in Premenopausal Women With Estrogen Receptor-Positive, HER2-Negative Breast Cancer

Trial Profile

preEMBER: A Phase 2, Open-label Study Evaluating Imlunestrant in Premenopausal Women With Estrogen Receptor-Positive, HER2-Negative Breast Cancer

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Jan 2026

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At a glance

  • Drugs Imlunestrant (Primary) ; Goserelin; Tamoxifen
  • Indications HER2 negative breast cancer
  • Focus Therapeutic Use
  • Acronyms PreEMBER
  • Sponsors Eli Lilly and Company

Most Recent Events

  • 15 Jan 2026 Planned End Date changed from 1 Jan 2029 to 1 Dec 2029.
  • 15 Jan 2026 Planned primary completion date changed from 1 Dec 2028 to 1 Jan 2029.
  • 07 Jan 2026 Planned initiation date changed from 1 Dec 2025 to 1 Jan 2026.

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