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A Phase I/II, Open-label, Multicenter Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of the TEAD Inhibitor TYK-01054 Capsules in Patients With Locally Advanced or Metastatic Advanced Solid Tumors

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Trial Profile

A Phase I/II, Open-label, Multicenter Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of the TEAD Inhibitor TYK-01054 Capsules in Patients With Locally Advanced or Metastatic Advanced Solid Tumors

Status: Not yet recruiting
Phase of Trial: Phase I/II

Latest Information Update: 16 Jan 2026

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At a glance

  • Drugs TY 1054 (Primary)
  • Indications Malignant-mesothelioma; Solid tumours
  • Focus Adverse reactions
  • Sponsors TYK Medicine

Most Recent Events

  • 22 Dec 2025 The protocol has been amended to change in treatment arm size.
  • 22 Dec 2025 New trial record

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