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A Single-arm, Multicenter, Open-label, Phase I/II Trial of Allo-QuadCAR01-T, an Allogeneic CAR-T-cell Therapy Targeting CD19 and CD20, for the Treatment of Relapsed or Refractory B-cell Malignancies

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Trial Profile

A Single-arm, Multicenter, Open-label, Phase I/II Trial of Allo-QuadCAR01-T, an Allogeneic CAR-T-cell Therapy Targeting CD19 and CD20, for the Treatment of Relapsed or Refractory B-cell Malignancies

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 27 Jan 2026

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At a glance

  • Drugs AVC 203 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms QUADvance
  • Sponsors AvenCell Therapeutics

Most Recent Events

  • 22 Jan 2026 Status changed from not yet recruiting to recruiting.
  • 22 Dec 2025 New trial record

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