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A Phase 1b/2 Study of ASP2998 as Monotherapy and in Combination With Standard Therapies in Participants With Locally Advanced Unresectable or Metastatic Solid Tumors

Trial Profile

A Phase 1b/2 Study of ASP2998 as Monotherapy and in Combination With Standard Therapies in Participants With Locally Advanced Unresectable or Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 12 Jun 2026

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At a glance

  • Drugs ASP 2998 (Primary) ; Carboplatin; Enfortumab vedotin; Pembrolizumab
  • Indications Adenocarcinoma; Bladder cancer; Carcinoma; Gastric cancer; HER2 negative breast cancer; Non-small cell lung cancer; Oesophageal cancer; Pelvic cancer; Renal cancer; Solid tumours; Transitional cell carcinoma; Ureteral neoplasms; Urethral cancer; Urogenital cancer
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Astellas Pharma Global Development

Most Recent Events

  • 18 May 2026 According to Astellas Pharma media release, company will present Poster Presentation from this study at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting taking place May 29 - June 2 in Chicago May 30, 2026, 1:30 PM-4:30 PM CDT
  • 29 Jan 2026 Status changed from not yet recruiting to recruiting.
  • 23 Dec 2025 New trial record

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