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A Phase 2 Randomized, Double-blind, Placebo-Controlled Study to Assess the Safety and Efficacy of MTX-474 in the Treatment of Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

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Trial Profile

A Phase 2 Randomized, Double-blind, Placebo-Controlled Study to Assess the Safety and Efficacy of MTX-474 in the Treatment of Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 13 Jan 2026

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At a glance

  • Drugs MTX-474 (Primary)
  • Indications Diffuse scleroderma
  • Focus Adverse reactions
  • Acronyms EncompaSSc
  • Sponsors Mediar Therapeutics

Most Recent Events

  • 07 Jan 2026 According to Mediar Therapeutics media release, company announced an oversubscribed $76 million Series B financing. The financing will further support advancement of this trial.
  • 23 Dec 2025 New trial record

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